WASHINGTON – The Supreme Court is allowing nationwide enforcement of a new Trump administration rule that prevents most Central American migrants from seeking asylum in the United States.

The justices’ order late Wednesday temporarily undoes a lower court ruling that had blocked the new asylum policy in some states along the southern border. The policy is meant to deny asylum to anyone who passes through another country on the way to the U.S. without seeking protection there.

Most people crossing the southern border are Central Americans fleeing violence and poverty. They are largely ineligible under the new rule, as are asylum seekers from Africa, Asia and South America who arrive regularly at the southern border.

The shift reverses decades of U.S. policy. The administration has said that it wants to close the gap between an initial asylum screening that most people pass and a final decision on asylum that most people do not win.

“BIG United States Supreme Court WIN for the Border on Asylum!” President Donald Trump tweeted.

Justices Ruth Bader Ginsburg and Sonia Sotomayor dissented from the high-court’s order.

“Once again, the Executive Branch has issued a rule that seeks to upend longstanding practices regarding refugees who seek shelter from persecution,” Sotomayor wrote.

The legal challenge to the new policy has a brief but somewhat convoluted history. U.S. District Judge Jon Tigar in San Francisco blocked the new policy from taking effect in late July. A three-judge panel of the 9th U.S. Circuit Court of Appeals narrowed Tigar’s order so that it applied only in Arizona and California, states that are within the 9th Circuit.

That left the administration free to enforce the policy on asylum seekers arriving in New Mexico and Texas. Tigar issued a new order on Monday that reimposed a nationwide hold on asylum policy. The 9th Circuit again narrowed his order on Tuesday.

The high court action allows the Republican administration to impose the new policy everywhere while the court case against it continues.

It’s unclear how quickly the policy will be rolled out and how exactly it fits in with the other efforts by the administration to restrict border crossings and tighten asylum rules.

For example, thousands of people are waiting on lists at border crossings in Mexico to claim asylum in the U.S. And acting U.S. Customs and Border Protection Commissioner Mark Morgan said Thursday that 45,000 people have been turned back to Mexico to wait out their asylum claims.

Asylum seekers must pass an initial screening called a “credible fear” interview, a hurdle that a vast majority clear. Under the new policy, they would fail the test unless they sought asylum in at least one country they traveled through and were denied. They would be placed in fast-track deportation proceedings and flown to their home countries at U.S. expense.

The American Civil Liberties Union lawyer who is representing immigrant advocacy groups in the case, Lee Gelernt, said: “This is just a temporary step, and we’re hopeful we’ll prevail at the end of the day. The lives of thousands of families are at stake.”

Morgan said Trump and his administration are “doing everything that they can” to address what he described as the crisis on the U.S. border with Mexico.

Migrants with valid claims “should be seeking help and asylum from the first country they come in contact with,” Morgan said Thursday on Fox News Channel’s “Fox and Friends.” ‘’They shouldn’t be paying the cartels thousands of dollars and risking their lives to take a 1,000-mile journey across several countries to get help. We want them to get help and seek asylum in the first country they get to.”

Justice Department spokesperson Alexei Woltornist said the agency was “pleased that the Supreme Court intervened in this case,” adding, “This action will assist the Administration in its objectives to bring order to the crisis at the southern border, close loopholes in our immigration system, and discourage frivolous claims.”

Associated Press writer Colleen Long contributed to this report.